HEPA Filter Testing &
Replacement Services

Request a Quote

HEPA Filter Testing &
Replacement Services

Request a quote

Health Systems Sciences (HSS) — Ensuring Clean Air and Critical Containment Performance

HSS provides HEPA filter integrity testing, leak scanning, diagnostics, and replacement support for cleanrooms, sterile compounding facilities, laboratories, hospital isolation rooms, and controlled environments.

We verify that HEPA filtration and air handling systems are performing as required to protect products, personnel, and clinical operations.

As a Service-Disabled Veteran–Owned Small Business (SDVOSB), HSS supports VA Medical Centers, DoD research & healthcare environments, hospital pharmacies, and commercial cleanrooms nationwide.

Core HEPA Testing Services

Core HEPA Testing Services

Integrity & Leak Testing

PAO / DOP scan testing of installed HEPA filters

Leak identification at filter media, gasket, and housing

Airflow distribution & uniformity assessment

Sealing and frame seating verification

Performance evaluation after cleaning or maintenance

Airflow Performance Checks

Air change rate (ACH) verification

Airflow velocity & diffuser balancing

Pressure differential and directional airflow validation

Temperature & humidity performance monitoring

Room & Hood Integration

Cleanroom (ISO 5 / 7 / 8) HEPA performance verification

PEC / BSC / Laminar Flow Hood airflow integrity

USP 797 sterile compounding zones

USP 800 hazardous drug negative-pressure rooms

Technician inspecting ceiling ventilation system in a cleanroom with a sampling device.

HEPA Filter Replacement Support

HSS can coordinate and oversee replacement when required:

  • Identify the correct HEPA specification by model, flow rating, and efficiency
  • Coordinate with approved OEM or HVAC suppliers
  • Oversee removal and installation procedures
  • Perform post-replacement certification testing to confirm compliance

We do not sell filters, which means our recommendations are objective and based only on performance requirements.

Standards & Compliance Alignment

Standards & Compliance Alignment

Our HEPA testing follows:

Our HEPA testing follows:

  • ISO 14644 Cleanroom Performance Standards
  • NSF/ANSI 49 Biological Safety Cabinet Requirements
  • CETA CAG-003-2006 Cleanroom & PEC Certification
  • ASHRAE & CDC Healthcare Airflow Guidelines

Ensures readiness for:

  • State Board of Pharmacy
  • CAP Laboratory Accreditation
  • Joint Commission
  • VA / DoD Environmental Safety Reviews

Ensures readiness for:

  • State Board of Pharmacy
  • CAP Laboratory Accreditation
  • Joint Commission
  • VA / DoD Environmental Safety Reviews

Facility Types Served

Facility Types Served

Hospital Pharmacies & Cleanrooms

Oncology & Infusion Centers

Sterile Processing Environments

VA & DoD Medical Centers & Research Labs

Academic & Government Research Labs

Biotechnology & Pharmaceutical Cleanrooms

Why Work With HSS

Why Work With HSS

Benefit

  • Reliable, accurate, standards-based testing.
  • We do not sell filters or equipment — no conflict of interest.
  • Consistent support for multi-site healthcare systems.
  • Practical guidance, easy for Facilities & QA to implement.
  • Meets federal contracting and subcontracting requirements.

Strength

  • Experienced Cleanroom & Equipment Specialists
  • Unbiased Recommendations
  • Clear, Actionable Reports
  • Nationwide Service
  • SDVOSB